Cancer Res; 79 (13 Supplement): 1642 (2019). [AACR Annual Meeting 2019, March 29-April 3 2019, Atlanta, Georgia]

Poster presentation on our preliminary results showing that epithelial- and stromal-domain expression and co-expression diversity of the biomarkers captured by highly multiplexed imaging predict risk of CRC recurrence and allow us to infer epithelial and stromal-domain protein networks specific to the risk-of-recurrence from the underlying signaling networks.

Cell Reports; 24(4): 873-882 (2018).

As a part of this work, we developed a nuclei segmentation method for stochastic optical reconstruction microscopy that avoids segmentation getting stuck in local minima due to numerous and distinct chromatin clusters within the nuclei reconstructed using localization microscopy.