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March 1, 2019

Spatial proteomics with hyperplexed fluorescence imaging predicts risk of colorectal cancer recurrence and infers recurrence-specific protein-protein networks

S. Uttam, A.M. Stern, S. A. Furman, F. Pullara, F. Ginty, D. L. Taylor, S. C. Chennubhotla

Cancer Res; 79 (13 Supplement): 1642 (2019). [AACR Annual Meeting 2019, March 29-April 3 2019, Atlanta, Georgia]

Poster presentation on our preliminary results showing that epithelial- and stromal-domain expression and co-expression diversity of the biomarkers captured by highly multiplexed imaging predict risk of CRC recurrence and allow us to infer epithelial and stromal-domain protein networks specific to the risk-of-recurrence from the underlying signaling networks.